Advanced Skin Recovery:
Featuring Humanized Type III Collagen
for post-procedure skin care.
Advanced Skin Recovery
Featuring Humanized Type III Collagen for post-procedure skin care.
Soothe, hydrate, and rejuvenate sensitive, compromised and injured skin with Colsigen - for all skin types.
A plant- based sheet mask with advanced fabric technology to conform to facial contours, helping to create a barrier that moisturizes evenly and ensures comfort during use.
Powered by nitrogen technology, refreshing hydrating facial spray, ideal for daily use and on-the-go hydration, plane safe as it does not contain butane, or other flammable gases.
- Human-sequence type III collagen
- Medical-grade, high purity, low endotoxin
- Non-animal, biotech manufacturing
- Supports the skin’s moisture barrier function
- Streamlined composition for high tolerability & low reactivity
- Gentle enough for everyday use on all types of skin
Registered FDA Class I Medical Device
Colsigen® Intended Use
Colsigen® products are a transient protective barrier, which improves hydration and supports skin repair. They are intended to be used following cosmetic procedures such as:
- Laser resurfacing (ablative and fractional)
- Microdermabrasion
- Microneedling
- Superficial peels
Gentle enough for everyday use on all types of skin, including dry, irritated, sensitive, or compromised skin in both adults, and children.
Colsigen Refresh™ Application
1. Cleanse your face thoroughly with lukewarm water.
2. Apply the mask gently to your clean, dry skin.
3. Relax for 20 minutes while the mask works.
4. Allow to absorb naturally or pat in gently for extra hydration and glow.
Colsigen Mist™ Application
1. Cleanse your face thoroughly with lukewarm water.
2. Hold the bottle 15–20 cm away from your face. Spray evenly across the skin, keeping eyes closed.
3. Allow to absorb naturally or pat in gently for extra hydration and glow.
Application Tips
- Use at room temp; if stinging, gently warm the unopened sachet in hands before application.
- Apply Colsigen Mist™ to the skin during the healing phase to relieve itchiness, dryness, and discomfort.
- Use the ColsigenMist™ before applying the mask to pre-hydrate the skin and enhance overall hydration comfort after treatment.
AMWC 2026 Workshop -
A live demonstration of the benefits of the ColsigenreFresh™ mask
Watch the recording of the live workshop held as part of AMWC 2026, during which Professor Leonardo Marini and Dr. Susanna Marini presented the benefits and application of the ColsigenreFresh™ mask following laser procedures, as part of a practical two-step recovery protocol designed to support barrier repair, enhance patient comfort, and streamline clinic workflow integration.
Do you have questions about our Colsigen® products? Check our FAQ!
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